CD41分子

CD41 分子 ? CD41 常用單克隆抗體或代號： PBM6.4,PL273(integrin a Ⅱb) 主要表達細胞： Pt,Meg [Pt] 分子質量(kDa)和結構： gp120/23 功??? 能： 血小板凝集和活化Fb,結合ECM(FB,vWF)的受體,與CD61組成二聚體 ? CD41 Aka platelet GPIIb Receptor for fibrinogenin, von Willebrand factor and fibronectin Mutations cause thrombasthenia Positive staining (normal): platelets, megakaryocytes Positive staining (disease): AML M7, blasts in transient myeloproliferative disorder ?