Models of Acute Inflammation in the Ear

Methods were earlier described (1 ) for the determination of proinflammatory mediators and biochemical markers, models of acute inflammation and pain (use of implanted sponges to study the acute inflammatory response, pleurisy and pouch models, and so on), models of nonarthritic inflammatory disorders and tissue injury (cutaneous models, eye models, models of acute pulmonary inflammation, animal models of inflammatory bowel disease, and so on), and animal models of arthritis (rat adjuvant arthritis, chronic remittent erosive arthritis, monoarticular antigen-induced arthritis, and cartilage proteoglycan-induced arthritis).