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  • 實驗方法> 實驗動物技術> 實驗動物總則>Development and Use of TCR Transgenic Mice for Malaria Immunology Research

    Development and Use of TCR Transgenic Mice for Malaria Immunology Research

    關鍵詞: development tcr transgenic mice來源: 互聯網

    T-cell receptor transgenic mice are powerful tools to study T cell responses to malaria parasites. They allow for a population of antigen specific T cells to be monitored during developing responses to immunization or parasite infection; this makes them particularly useful to study fundamental aspects of T cell activation, differentiation, and migration in different tissue compartments. Moreover, the use of these cells allows for a thorough analysis of the mechanisms of antiparasite activity by T cells.

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