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  • 實驗方法> 實驗動物技術> 實驗動物總則>Methods for the Identification of Host Receptors for Shiga Toxin

    Methods for the Identification of Host Receptors for Shiga Toxin

    關鍵詞: methods identification host receptors來源: 互聯網

    The Shiga toxin receptor glycolipid Gb3 (globotriaosylceramide) is also known as the pk blood group antigen (1 ) and as CD77, a germinal center B-cell differentiation antigen (2 ). Tissue localization of Gb3 is associated with sites of Stx-induced pathology in animal models (3 –5 ) and in humans (6 ) and, as such, is a major determinant of Stx1-induced disease.

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