Biosensing儀器推出全球首款用于膜蛋白相互作用研究的商用表面等離子體共振顯微鏡系統

發布時間： Feb 22， 2017

亞利桑那州坦佩--（美國商業資訊生物傳感儀器公司（BI）推出了SPRm 200，這是世界上第一個商用表面等離子體共振顯微鏡（SPRM）系統。新型 SPRm 200 是市場上唯一可實現無標記的科學解決方案體外測量單個細胞在其天然環境中的結合反應和動力學。通過提供使用傳感器芯片上生長的細胞研究分子相互作用的能力，這個新穎的系統重新定義了SPR技術的前沿。研究人員現在可以簡單地選擇一個細胞，并直接使用一臺儀器進行結合親和力和動力學研究。

“許多學術實驗室一直在開發SPR系統，以獲得更多關于膜蛋白的生物學相關結合信息，但自制解決方案很難使用。現在，借助SPRm 200，生物傳感儀器為研究候選藥物和細胞靶標提供了一種易于使用的解決方案。

“許多學術實驗室一直在開發SPR系統，以獲得更多關于膜蛋白的生物學相關結合信息，但自制解決方案很難使用。現在，借助SPRm 200，生物傳感儀器為研究候選藥物和細胞靶標提供了一種易于使用的解決方案，“BI研發總監Nguyen Ly博士說。“我們的合作者對新系統能夠量化膜蛋白在其天然細胞環境中的結合親和力和動力學以及進行不同細胞的異質性統計分析的能力感到非常興奮。膜蛋白占目前藥物靶標的一半以上，因此能夠獲得體外測量確實加快了藥物和疫苗的開發。

SPRm 200 系統采用最先進的技術，無縫集成了光學成像和 SPR 技術，為研究人員提供了兩者的優勢。使用BI的新ImageSPR?軟件，可以實時映射和量化每個細胞膜的結合親和力和動力學反應。該系統的大光學視場和出色的SPR分辨率使研究人員能夠測量單個細胞或多個細胞的局部結合活性和動力學。

SPRm 200 在設計時考慮了應用靈活性，還可用于測量病毒、細菌和納米顆粒的納米級結合活性。

要觀看 SPRm 200 產品視頻，請轉到https://youtu.be/c4SrPzfOZNE.

關于生物傳感儀器

生物傳感儀器公司（BI）是2016年研發獎獲得者，提供基于表面等離子體共振（SPR）的創新和高性能無標記分子相互作用分析儀器。BI SPR 儀器用于生命科學、藥物發現、抗體表征、生物傳感器和電化學應用，以測量生物分子的親和力和動力學。

有關 BI 的其他信息，請訪問www.biosensingusa.com.

Biosensing Instrument Introduces World’s First Commercially Available Surface Plasmon Resonance Microscopy System For Membrane Protein Interactions Research

Published: Feb 22, 2017

TEMPE, Ariz.--(BUSINESS WIRE)--Biosensing Instrument Inc (BI) introduced the SPRm 200, the world’s first commercially available surface plasmon resonance microscopy (SPRM) system. The new SPRm 200 is the only scientific solution on the market that enables label-free in vitro measurement of binding reactions and kinetics of individual cells in their native environment. By providing the ability to study molecular interactions using cells grown on the sensor chip, this novel system redefines the frontier of SPR technology. Researchers can now simply select a cell and directly perform binding affinity and kinetic studies all with one instrument.

“Many academic laboratories have been developing SPR systems to obtain more biologically relevant binding information about membrane proteins, but homemade solutions are difficult to use. Now, with the SPRm 200, Biosensing Instrument offers an easy-to-use solution for investigating drug candidates and cell targets”

“Many academic laboratories have been developing SPR systems to obtain more biologically relevant binding information about membrane proteins, but homemade solutions are difficult to use. Now, with the SPRm 200, Biosensing Instrument offers an easy-to-use solution for investigating drug candidates and cell targets,” said Dr. Nguyen Ly, Director of Research and Development at BI. “Our collaborators are very excited by the new system’s ability to quantify binding affinity and kinetics of membrane proteins in their native cellular environment and to perform heterogeneity statistical analysis of different cells. Membrane proteins account for more than half of present drug targets, so having access to in vitro measurement really expedites drug and vaccine development.”

The SPRm 200 system’s state-of-the-art technology seamlessly integrates optical imaging and SPR technology, affording researchers the benefits of both. Using BI’s new ImageSPR? software, the binding affinity and kinetic responses of each cell membrane can be mapped and quantified in real-time. The system’s large optical field-of-view and excellent SPR resolution allows researchers to measure the local binding activities and kinetics of a single cell or multiple cells.

Engineered with application flexibility in mind, the SPRm 200 can also be utilized to measure the nanometer-scale binding activities of viruses, bacteria, and nanoparticles.

To watch the SPRm 200 product video, go to https://youtu.be/c4SrPzfOZNE.

About Biosensing Instrument

Biosensing Instrument Inc (BI), a 2016 R&D Award Winner, supplies innovative and high-performance label-free molecular interaction analysis instruments based on Surface Plasmon Resonance (SPR). BI SPR instruments are used in the life science, drug discovery, antibody characterization, biosensor, and electrochemistry applications to measure the affinity and kinetics of biomolecules.

Additional information about BI can be found at www.biosensingusa.com.

Biosensing Instrument, Inc.
Akemi Ueki, 480-491-2777
info2bi@biosensingusa.com