HORIBA Scientific 很高興地宣布推出 OpenPlex，這是一個靈活的研究平臺，用于以多重格式實時分析無標記分子相互作用。

OpenPlex使用表面等離子體共振成像（SPRi）來監測分子與固定在傳感器芯片上的受體陣列的結合。它可以提供相互作用的定性（是/否結合）和定量信息，例如濃度，親和力（KD），結合和解離率（kon，koff）。可以表征和量化涉及蛋白質、DNA、RNA、寡糖、活細胞、聚合物或納米顆粒的分子相互作用。

OpenPlex 是 SPRi-Lab+ 的演變，SPRi-Lab+ 是 HORIBA Scientific 的臺式柔性無標記儀器。該儀器設計操作簡單，適用于物理化學、生物化學、生物學和納米技術等多種應用。

提供不同的流通池配置，使無標記分子相互作用分析與熒光或電化學相結合變得更加容易。這種新設計將促進從納米技術到生物醫學研究的前沿研究。

Real Time Binding Analysis Made Easy with OpenPlex

HORIBA Scientific is pleased to announce the launch of OpenPlex, a flexible research platform for the real time analysis of label-free molecular interactions in a multiplex format.

OpenPlex uses Surface Plasmon Resonance imaging (SPRi) to monitor the binding of molecules to an array of receptors immobilized on a sensor chip. It can give qualitative (Yes/No binding) and quantitative information of the interactions such as concentration, affinity (KD), association and dissociation rates (kon, koff). Molecular interactions involving proteins, DNA, RNA, oligosaccharides, living cells, polymers or nanoparticles can be characterized and quantified.

OpenPlex is the evolution of SPRi-Lab+, the bench-top flexible label-free instrument from HORIBA Scientific. This instrument was designed for simple operation and is adapted to multiple applications covering physico-chemistry, biochemistry, biology and nanotechnology.

Different flow cell configurations are available, making the combination of label-free molecular interaction analysis to fluorescence or electrochemistry even easier. This new design will facilitate cutting-edge research, from nanotechnologies to biomedical research.